Isovaleryl chloride → 2-(2-Methylpropyl)-1,3-thiazole-4-carboxylic acid

HRID 1255291

반응식

CC[CH:3]([C:6]1[S:7][CH:8]=[C:9]([C:11]([O:13]CC)=[O:12])[N:10]=1)[CH2:4][CH3:5].[CH3:16]C(C)CC(Cl)=O>>[CH2:3]([C:6]1[S:7][CH:8]=[C:9]([C:11]([OH:13])=[O:12])[N:10]=1)[CH:4]([CH3:5])[CH3:16]

참가 물질

반응물 2

HCID 66054Isovaleryl chloride

HCID 57989261Ethyl 2-(pentan-3-yl)thiazole-4-carboxylate

생성물 1

HCID 235881542-(2-Methylpropyl)-1,3-thiazole-4-carboxylic acid

실험 절차

Prepared by the method of Carboxylic Acid 3, using 3-methylbutanoyl chloride (10 mL) in place of 2-ethylbutanoyl chloride in step a. Yield 3.8 g.

출처 및 근거

ORD 기록: ord-64196a341d2244d7929ccac35d225a7d
출처 데이터셋: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08455483B2

연결된 노트

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