Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N'-Dimethylethylenediamine → 1-[5-Phenyl-6-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-propan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N'-Dimethylethylenediamine | HCID 8070 | — |
| 반응물 | Triethylaluminum | HCID 16682930 | — |
| 반응물 | Ethyl 5-phenyl-6-(4-trifluoromethylphenyl)-pyridine-2-carboxylate | HCID 68407826 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-[5-Phenyl-6-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-propan-1-one | HCID 25033168 | — |
반응 단계
Following General Procedure O, 5-phenyl-6-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid ethyl ester (Compound 29, 292 mg, 0.71 mmol) in toluene (5 ml), N,N′-dimethylethylenediamine (DMEDA, 76 mg, 0.86 mmol) and triethylaluminum (2.4 ml, 0.35 mmol, 1 M in hexane) were reacted to produce the title compound as a oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728014B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-fec3f79e1b134d3c9cf24eaca51232e1 |
| 출처 메모 | uspto-grants-2010_06 |