Imidazole → 13,13,14,14-Tetramethyl-3,6,9,12-tetraoxa-13-silapentadecan-1-ol

HRID 1255966노트

반응식

HRID 1255966 반응식
[C:1]([Si:5]([CH3:14])([CH3:13])[O:6][CH2:7][CH2:8][O:9][CH:10](O)[CH3:11])([CH3:4])([CH3:3])[CH3:2].[CH2:15]([OH:27])[CH2:16][O:17][CH2:18][CH2:19][O:20]CCOCCO.CC([Si](Cl)(C)C)(C)C.N1C=CN=C1>CN(C=O)C>[C:1]([Si:5]([CH3:14])([CH3:13])[O:6][CH2:7][CH2:8][O:9][CH2:10][CH2:11][O:27][CH2:15][CH2:16][O:17][CH2:18][CH2:19][OH:20])([CH3:4])([CH3:3])[CH3:2]

참가 물질

6

반응물 4

HCID 795ImidazoleHCID 8200Tetraethylene GlycolHCID 28928tert-Butyldimethylsilyl chlorideHCID 866188412-(tert-Butyl-dimethyl-silanyloxy)-ethoxyl-ethanol

생성물 1

HCID 1482766913,13,14,14-Tetramethyl-3,6,9,12-tetraoxa-13-silapentadecan-1-ol

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

Compound 28b was prepared according to the procedure described hereinabove for Compound 28a, using tetraethylene glycol (6 grams, 30 mmol), TBDMSCl (3 grams, 20 mmol), and imidazole (1.4 grams, 20 mmol) in DMF (24 ml), yielding 3.79 grams of the product (41% yield).

출처 및 근거

ORD 기록
ord-0c06a23abbe544bf87e80226b614379a
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08461166B2

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