Isopropylamine → N-Isopropyl-2-Nitro-4-(Trifluoromethyl)Aniline
반응식
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].CN1CCCC1=O.[CH:22]([NH2:25])([CH3:24])[CH3:23]>O>[CH:22]([NH:25][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13])([CH3:24])[CH3:23]참가 물질
5
실험 절차
To a mixture of 5.23 g of 4-fluoro-3-nitro-benzo trifluoride and 25 ml of N-methylpyrrolidone was added 3.69 g of isopropylamine under ice cool, and the mixture was stirred for 1 hour at room temperature. The reaction mixture was poured into water, the deposited solid was collected by filtration. This solid was washed with water, then, dried under reduced pressure to obtain 5.90 g of N-isopropyl-2-nitro-4-trifluoromethylaniline.
후처리
- temperaturecool
- filtrationthe deposited solid was collected by filtration
- washThis solid was washed with water
- customdried under reduced pressure
출처 및 근거
- ORD 기록
- ord-e0259394ecd54aa9909803d203401100
- 출처 데이터셋
- uspto-grants-2013_06
- 특허 번호
- US08461181B2
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