HCID 57619177, 화합물 → HCID 57619439, 화합물
반응식
C(OC(=O)[N:7]([C:16]1[CH:21]=[CH:20][C:19](Br)=[C:18]([F:23])[N:17]=1)[CH2:8][C:9]1[CH:10]=[N:11][CH:12]=[C:13]([F:15])[CH:14]=1)(C)(C)C.C(OC(=O)[N:31]([C:40]1[CH:45]=[CH:44][C:43](Br)=[C:42](F)[N:41]=1)[CH2:32][C:33]1[CH:38]=CC(Cl)=CC=1)(C)(C)C>>[F:15][C:13]1[CH:14]=[C:9]([CH2:8][NH:7][C:16]2[CH:21]=[CH:20][C:19]([CH2:38][C:33]3[C:45]4[C:40](=[N:41][CH:42]=[CH:43][CH:44]=4)[NH:31][CH:32]=3)=[C:18]([F:23])[N:17]=2)[CH:10]=[N:11][CH:12]=1참가 물질
3
실험 절차
was prepared following the protocol of Scheme 201, replacing 5-bromo-6-fluoro-pyridin-2-yl)-(5-fluoro-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester 631 with (5-Bromo-6-fluoro-pyridin-2-yl)-(4-chloro-benzyl)-carbamic acid tert-butyl ester 637 (prepared as described in Example 60) in Step 4. MS (ESI) [M+H+]+=391.9.
후처리
- customwas prepared
출처 및 근거
- ORD 기록
- ord-7c6e6799578b43a2951c95e4e558de4f
- 출처 데이터셋
- uspto-grants-2013_06