HCID 68506138, 화합물 → HCID 68507622, 화합물

HRID 1256904노트

반응식

HRID 1256904 반응식
[CH2:1]([N:3](CC)[C:4](=[O:32])[CH:5]([CH2:22][C:23]1[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][CH:24]=1)[C:6]([NH:8][S:9]([C:12]1[CH:21]=[CH:20][C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=1)(=[O:11])=[O:10])=[O:7])[CH3:2]>C(N)C.CO>[CH2:1]([NH:3][C:4](=[O:32])[CH:5]([CH2:22][C:23]1[CH:24]=[CH:25][C:26]([N+:29]([O-:31])=[O:30])=[CH:27][CH:28]=1)[C:6]([NH:8][S:9]([C:12]1[CH:21]=[CH:20][C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=1)(=[O:10])=[O:11])=[O:7])[CH3:2]

참가 물질

3

반응물 1

HCID 68506138HCID 68506138, 화합물

생성물 1

HCID 68507622HCID 68507622, 화합물수율 54.4%

시약·촉매·용매 1

HCID 86635283HCID 86635283, 화합물용매

실험 절차

In the same manner as in Example 1 (4), a crude product was obtained using the compound (400 mg) obtained in Example 6 (4) and 40% ethylamine-methanol solution (500 μL). This was purified by silica gel column chromatography to give the title compound (205 mg) as a white powder.

후처리

  1. customThis was purified by silica gel column chromatography

출처 및 근거

ORD 기록
ord-44860af934434ff4ac6dbc9c0846a3f8
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08461209B2

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