Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylamine → 4,5-Dichloro-n-methyl-2-nitroaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | 1,2-Dichloro-4-fluoro-5-nitrobenzene | HCID 533951 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4,5-Dichloro-n-methyl-2-nitroaniline | HCID 289317 | — |
반응 단계
1,2-Dichloro-4-fluoro-5-nitrobenzene (5.00 g, 23.8 mmol) in DMF (5.0 mL) was added to methylamine (10% in toluene, 80.0 g, 258 mmol) and stirred at rt overnight. The reaction mixture was filtered through a pad of ALOX B, washed with DMF/MeOH and concentrated to give the sub-title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08466186B2 |
| 출처 데이터셋 | uspto-grants-2013_06 |
| ORD ID | ord-d61c36bcae2d495787174dc822b42dd2 |
| 출처 메모 | uspto-grants-2013_06 |