1,1'-Thiocarbonyldi-2(1H)-pyridone → HCID 86646343, 화합물

HRID 1258634노트

반응식

HRID 1258634 반응식
[C:1](N1C=CC=CC1=O)(N1C=CC=CC1=O)=[S:2].[NH2:17][C:18]1[CH:19]=[C:20]([CH:29]=[CH:30][C:31]=1[Cl:32])[CH2:21][NH:22][C:23](=[O:28])[C:24]([CH3:27])([CH3:26])[CH3:25]>C(Cl)Cl>[Cl:32][C:31]1[CH:30]=[CH:29][C:20]([CH2:21][NH:22][C:23](=[O:28])[C:24]([CH3:27])([CH3:26])[CH3:25])=[CH:19][C:18]=1[N:17]=[C:1]=[S:2]

참가 물질

4

반응물 2

HCID 8531621,1'-Thiocarbonyldi-2(1H)-pyridoneHCID 66765386N-(3-amino-4-chlorobenzyl)pivalamide

생성물 1

HCID 86646343HCID 86646343, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

1,1′-Thiocarbonyldi-2-pyridone (2.12 g, 9.1 mmol) was added to a mixture of N-(3-amino-4-chlorobenzyl)-2,2-dimethyl-propionamide (2.00 g, 8.3 mmol) and DCM (60 mL) and stirred at rt for 1.5 h. The mixture was filtered over silica gel. The organic layer was concentrated to give the sub-title compound.

후처리

  1. filtrationThe mixture was filtered over silica gel
  2. concentrationThe organic layer was concentrated

출처 및 근거

ORD 기록
ord-7125d667e7ff480ebce03b54f597e544
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08466186B2

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