3-Amino-3-(4-chlorophenyl)propanoic acid → Methyl 3-amino-3-(4-chlorophenyl)-propionate

HRID 1258796노트

반응식

HRID 1258796 반응식
N[CH:2](C1C=CC(OC)=C(OC)C=1)CC(O)=O.[NH2:17][CH:18]([C:23]1[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=1)[CH2:19][C:20]([OH:22])=[O:21]>>[NH2:17][CH:18]([C:23]1[CH:24]=[CH:25][C:26]([Cl:29])=[CH:27][CH:28]=1)[CH2:19][C:20]([O:22][CH3:2])=[O:21]

참가 물질

3

반응물 2

HCID 3441763-Amino-3-(4-chlorophenyl)propanoic acidHCID 5971823-Amino-3-(3,4-dimethoxyphenyl)propanoic acid

생성물 1

HCID 3704340Methyl 3-amino-3-(4-chlorophenyl)-propionate

실험 절차

The title compound was prepared following the method for preparing Intermediate 6 except that 3-amino-3-(3,4-dimethoxy-phenyl)-propionic acid was substituted with 3-amino-3-(4-chlorophenyl)propionic acid. 1H NMR (CDCl3): δ 7.24-7.32 (m, 5H), 4.38 (t, 1H, J=5 Hz), 3.65 (s, 3H), 2.61 (d, 2H, J=5 Hz), 1.80 (s, 2H).

출처 및 근거

ORD 기록
ord-62bf8f93fc24444984baef87acbfa5f7
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08466191B2

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