Hydroxylamine → HCID 45276554, 화합물

HRID 1258942노트

반응식

HRID 1258942 반응식
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([CH2:9][N:10]2[C:18]3[C:13](=[CH:14][CH:15]=[C:16]([C:19]([OH:21])=O)[CH:17]=3)[CH:12]=[CH:11]2)=[CH:5][CH:4]=1.[NH2:22][OH:23]>>[OH:23][NH:22][C:19]([C:16]1[CH:17]=[C:18]2[C:13]([CH:12]=[CH:11][N:10]2[CH2:9][C:6]2[CH:7]=[N:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[CH:14][CH:15]=1)=[O:21]

참가 물질

3

반응물 2

HCID 787HydroxylamineHCID 58213836HCID 58213836, 화합물

생성물 1

HCID 45276554HCID 45276554, 화합물

실험 절차

1-((6-Methoxypyridin-3-yl)methyl)-1H-indole-6-carboxylic acid was activated and coupled with NH2OH as described in Example 4, Step 3 to provide N-hydroxy-1-((6-methoxypyridin-3-yl)methyl)-1H-indole-6-carboxamide as a tan solid.

출처 및 근거

ORD 기록
ord-32cd62b916ef436e964a8619baa22648
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08466193B2

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