5-Fluoro-2-methylbenzyl bromide → HCID 68662395, 화합물

반응식

[NH2:1][C:2]1[N:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[Br:12][CH2:13][C:14]1[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:15]=1[CH3:21]>>[BrH:12].[Cl:11][C:8]1[CH:7]=[C:3]([C:4]([NH2:6])=[O:5])[C:2](=[NH:1])[N:10]([CH2:13][C:14]2[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:15]=2[CH3:21])[CH:9]=1

참가 물질

반응물 2

HCID 27746055-Fluoro-2-methylbenzyl bromide

HCID 668768832-Amino-5-chloronicotinamide

생성물 1

HCID 68662395HCID 68662395, 화합물

실험 절차

According to the method of Example 172, 2-amino-5-chloronicotinamide was reacted with 2-(bromomethyl)-4-fluoro-1-methylbenzene to give the title compound.

출처 및 근거

ORD 기록: ord-93af4d10f4364a2395a0e71f02b6c0ee
출처 데이터셋: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08470859B2

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