HCID 57701070, 화합물 → HCID 25267399, 화합물

반응식

C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]23[CH2:27][CH2:26][CH2:25][CH2:24][CH:16]2[O:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=23)=[CH:11][CH:10]=1)C1C=CC=CC=1.FC1C=CC=CC=1C1(C2C=CC(O)=CC=2)CCCCCC1=O>>[CH:20]1[C:19]2[C:15]3([C:12]4[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=4)[CH2:27][CH2:26][CH2:25][CH2:24][CH:16]3[O:17][C:18]=2[CH:23]=[CH:22][CH:21]=1

참가 물질

반응물 2

HCID 57701070HCID 57701070, 화합물

HCID 57701091HCID 57701091, 화합물

생성물 1

HCID 25267399HCID 25267399, 화합물

실험 절차

The title compound 961 was synthesized from compound 34 (10 mg) using the procedure described for the synthesis of compound 20. Purity LC MS/UV: m/z=265 (M−1) was confirmed. Yield: 7 mg (93%). 1H-NMR (400 MHz, CDCl3): δ ppm 7.26-7.20 (m, 2H), 7.17-7.11 (m, 1H), 6.87-6.84 (m, 3H), 6.80-6.77 (m, 2H), 4.83 (t, J=4.29, 4.29 Hz, 1H), 4.67 (s, 1H), 2.35-2.22 (m, 1H), 2.05-1.96 (m, 1H), 1.86-1.50 (m, 6H).

출처 및 근거

ORD 기록: ord-c89b5a314d55435aafdcb4065d77b909
출처 데이터셋: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08470872B2

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