5-(3,4-Dichlorobenzyl-carbamoyl)-thiophene-2-carboxylic acid → 5(3,4-Dichlorobenzylcarbamoyl)pyridine-2-carbonylchloride
반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][C:20]=1[Cl:21])[CH2:5][NH:6][C:7]([C:9]1[CH:10]=[CH:11][C:12]([C:15](O)=[O:16])=[N:13][CH:14]=1)=[O:8].[Cl:22]C1C=C(C=CC=1Cl)CNC(C1SC(C(O)=O)=CC=1)=O>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][C:20]=1[Cl:21])[CH2:5][NH:6][C:7]([C:9]1[CH:10]=[CH:11][C:12]([C:15]([Cl:22])=[O:16])=[N:13][CH:14]=1)=[O:8]참가 물질
3
실험 절차
Compound (13(b)) was treated in an analogous manner to compound (12(b)) in Example 12 to give 5(3,4-dichlorobenzylcarbamoyl)pyridine-2-carbonylchloride (13(c)) which was used crude in the next reaction.
출처 및 근거
- ORD 기록
- ord-52baa47682b942eabd003fbf7fca1a71
- 출처 데이터셋
- uspto-grants-2003_04
- 특허 번호
- US06541491B1
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