참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 반응물 | Methanesulfonic acid 2-(2-chloromethyl-phenyl)-ethyl ester | HCID 54328826 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 1-(Chloromethyl)-2-ethenylbenzene | HCID 89757 | 82% |
반응 단계
Dissolve methanesulfonic acid 2-(2-chloromethyl-phenyl)-ethyl ester (8.8 g, 35.4 mmol) in ether (80 mL) and cool to −35° C. Add potassium t-butoxide (10 g, 89 mmol) and stir for 30 minutes. Add water (50 mL) and ether (150 mL), extract, dry (Na2SO4) and purify by silica gel chromatography (2:3 methylene chloride/pentane) to give 1-chloromethyl-2-vinyl-benzene as a colorless oil (4.43 g, 82%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06544980B2 |
|---|
| 출처 데이터셋 | uspto-grants-2003_04 |
|---|
| ORD ID | ord-18cf2be087e047fbbc8e0f34bf08e9e2 |
|---|
| 출처 메모 | uspto-grants-2003_04 |
|---|
