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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1265084생성일: 2026년 10월 26일

trans-2-Phenylcyclopropyl isocyanate → 4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}-N-[(1R*,2S*)-2-phenylcyclopropyl]piperidine-1-carboxamide

https://huagongshe.com/reaction/1265084

반응식

참여 물질

역할이름HCID투입량
반응물trans-2-Phenylcyclopropyl isocyanateHCID 255285—
반응물2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amineHCID 12972962—
생성물4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}-N-[(1R*,2S*)-2-phenylcyclopropyl]piperidine-1-carboxamideHCID 20575808—

반응 단계

Using the method of Examples 54-65, trans-2-phenylcyclopropyl isocyanate was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 491.3139.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06545017B1
출처 데이터셋uspto-grants-2003_04
ORD IDord-3e4377aa165b4d8c96a5b93a5e0c3bba
출처 메모uspto-grants-2003_04