(5-Dimethylamino-4-fluoro-2-nitro-phenyl)-carbamic acid tert.-butyl ester → (2-Amino-5-dimethylamino-4-fluoro-phenyl)-carbamic acid tert.-butyl ester
반응식
[C:1]([O:5][C:6](=[O:21])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH3:16])[CH3:15])[C:11]([F:17])=[CH:10][C:9]=1[N+:18]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:21])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH3:16])[CH3:15])[C:11]([F:17])=[CH:10][C:9]=1[NH2:18])([CH3:4])([CH3:2])[CH3:3]참가 물질
3
실험 절차
The title compound was prepared from (5-dimethylamino-4-fluoro-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example C11) (4.88 g, 16 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a green solid (4.55 g).
출처 및 근거
- ORD 기록
- ord-1e9cfaaf08964802aade67834786209e
- 출처 데이터셋
- uspto-grants-2003_04
- 특허 번호
- US06544985B2
반응 노트
불러오는 중…