3-(2-Methyl-oxazol-4-yl)-benzoic acid methyl ester → 3-Oxo-3-[3-(2-methyl-oxazol-4-yl)-phenyl]-propionic acid tert-butyl ester
반응식
CO[C:3](=[O:16])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[N:11]=[C:12]([CH3:15])[O:13][CH:14]=2)[CH:5]=1.[C:17]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])(=[O:19])[CH3:18].[Li]>>[C:21]([O:20][C:17](=[O:19])[CH2:18][C:3](=[O:16])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[N:11]=[C:12]([CH3:15])[O:13][CH:14]=2)[CH:5]=1)([CH3:24])([CH3:23])[CH3:22]참가 물질
3
실험 절차
3-(2-Methyl-oxazol-4-yl)-benzoic acid methyl ester (1.02 g) was treated with lithium tert.-butyl acetate according to the general procedure K (method b) to give crude 3-oxo-3-(3-(2-methyl-oxazol-4-yl)-phenyl]-propionic acid tert -butyl ester (1.50 g) as a pale-yellow oil.
출처 및 근거
- ORD 기록
- ord-910a5396d0094940985622dbdf30b8ef
- 출처 데이터셋
- uspto-grants-2003_04
- 특허 번호
- US06544985B2