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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1266398생성일: 2026년 10월 27일

1-Amino-5-isopropylamino-pentan-3-ol → 5-[3-(3-Hydroxy-5-isopropylamino-pentyl)-ureido]-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazole-4-carboxylic acid amide

https://huagongshe.com/reaction/1266398

반응식

참여 물질

역할이름HCID투입량
반응물1-Amino-5-isopropylamino-pentan-3-olHCID 18550751—
반응물[4-Carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl esterHCID 54053016—
생성물5-[3-(3-Hydroxy-5-isopropylamino-pentyl)-ureido]-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazole-4-carboxylic acid amideHCID 10436135—

반응 단계

The title compound was prepared from [4-carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl ester and 1-amino-5-isopropylamino-pentan-3-ol by the procedure analogous to Example 1. MS (APCl, m/z): 504 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06548526B2
출처 데이터셋uspto-grants-2003_04
ORD IDord-8563207763a049f284eea8a558f277d3
출처 메모uspto-grants-2003_04