Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → HCID 86591308, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 4'-Trifluoromehtyl-biphenyl-2-carboxylic acid [4-[4-(3-cyano-benzyl)-piperazin-1-yl]-phenyl]-amide | HCID 9807315 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | HCID 86591308 | HCID 86591308 | — |
반응 단계
To a solution of 4′-trifluoromehtyl-biphenyl-2-carboxylic acid [4-[4-(3-cyano-benzyl)-piperazin-1-yl]-phenyl]-amide (0.2 g) in AcOEt (25 mL) was added 1N hydrochloric acid (0.9 mL) and the resulting solution was stirred at room temperature for 1.5 hours. The solution was then evaporated to dryness and the solid was recrystallized from AcOEt/hexane to give the title compound (0.18 g) as a white power.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06552022B1 |
| 출처 데이터셋 | uspto-grants-2003_04 |
| ORD ID | ord-52e919eeb25e4b04bcc1d41f968ca2f9 |
| 출처 메모 | uspto-grants-2003_04 |