Water → 4,4,5,5,6,6,7,7,7-Nonafluoroheptyl iodide

HRID 1267468노트

반응식

HRID 1267468 반응식
CS(O[CH2:6][CH2:7][CH2:8][C:9]([F:21])([F:20])[C:10]([F:19])([F:18])[C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13])(=O)=O.[I-:22].[Na+].O>CC(C)=O>[I:22][CH2:6][CH2:7][CH2:8][C:9]([F:21])([F:20])[C:10]([F:19])([F:18])[C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13]

참가 물질

5

반응물 3

HCID 962WaterHCID 5238Sodium IodideHCID 120167731-Methanesulfonyloxy-4,4,5,5,6,6,7,7,7-nonafluoroheptane

생성물 1

HCID 120167744,4,5,5,6,6,7,7,7-Nonafluoroheptyl iodide수율 87%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

1-Methanesulfonyloxy-4,4,5,5,6,6,7,7,7-nonafluoro-heptane (6.7 g, 18.8 mmol) and sodium iodide (8.5 g, 56.4 mmol) were stirred in acetone (400 ml) for 12 hours under heating. After the reaction was completed, water was added to the reaction mixture, which was then extracted with ether. The organic layer was washed with water and saturated aqueous sodium chloride, and then dried over anhydrous magnesium sulfate. The solvent was distilled off to give 1-iodo-4,4,5,5,6,6,7,7,7-nonafluoroheptane (6.33 g, Yield 87%) as a colorless oil.

후처리

  1. temperatureunder heating
  2. extractionwas then extracted with ether
  3. washThe organic layer was washed with water and saturated aqueous sodium chloride
  4. dry with materialdried over anhydrous magnesium sulfate
  5. distillationThe solvent was distilled off

출처 및 근거

ORD 기록
ord-fad63775b7ea4eff888fb5a2e2a253e6
출처 데이터셋
uspto-grants-2003_04
특허 번호
US06552069B1

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