Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Diphenylpyridine → (R)-N-[3-nitro-2-chlorophenyl]-2-hydroxy-2-methyl-3,3,3-trifluoropropanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Diphenylpyridine | HCID 72920 | — |
| 반응물 | (2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoic acid | HCID 2760712 | — |
| 반응물 | 2-Chloro-3-nitroaniline | HCID 14220016 | — |
| 생성물 | (R)-N-[3-nitro-2-chlorophenyl]-2-hydroxy-2-methyl-3,3,3-trifluoropropanamide | HCID 58964771 | — |
반응 단계
The title compound was prepared by the method of Example 6 using (R)-(+)-2-hydroxy-2-methyl-3,3,3-trifluoropropanoic acid (Method 3) and 2-chloro-3-nitroaniline (Tetrahedron, 1999, 56 (2), 165-173) except that 2,6-diphenylpyridine was used instead of 2,6-di-t-butylpyridine. NMR (CDCl3) 1.77 (s, 3H), 3.58 (s, 1H), 7.44 (t, 1H), 7.63 (d, 1H), 8.66 (d, 1H), 9.27 (s, 1H); m/z 311.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06552225B1 |
| 출처 데이터셋 | uspto-grants-2003_04 |
| ORD ID | ord-de58347e36eb4e578562f5ea0378103f |
| 출처 메모 | uspto-grants-2003_04 |