돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1268681생성일: 2026년 10월 27일

2-Amino-4-methylpyridine → 2-(4'-Chloropropoxy-3'-methoxyphenyl)-7-methylimidazo[1,2-a]pyridine hydrobromide

https://huagongshe.com/reaction/1268681

반응식

참여 물질

역할이름HCID투입량
반응물2-Amino-4-methylpyridineHCID 1533—
반응물alpha-Bromo-3'-methoxy-4'-chloropropoxyacetophenoneHCID 22015629—
용매EthanolHCID 702—
생성물2-(4'-Chloropropoxy-3'-methoxyphenyl)-7-methylimidazo[1,2-a]pyridine hydrobromideHCID 2201559870.5%

반응 단계

A solution of the product of Step B (1.44 g) and 2-amino-4-picoline (0.486 g) in ethanol (6 mL) was heated at 730 C for 1 hour. The reaction mixture was cooled to ambient temperature and evaporated to a yellow solid. The solid was stirred with 25 mL of dichloromethane for approximately 10 minutes. The mixture was filtered and the solid product collected to yield the title compound (1.3 g).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07199117B2
출처 데이터셋uspto-grants-2007_04
ORD IDord-182ef95a5673486687b03d92475e7293
출처 메모uspto-grants-2007_04