HCID 10989032, 화합물 → HCID 11096141, 화합물
반응식
CC1(C)[O:6][C@@H:5]([C@@H:7]2[C@@H:14]3[C@@H:10]([O:11][C:12]([CH3:16])([CH3:15])[O:13]3)[CH2:9][S:8]2)[CH2:4][O:3]1>CC(O)=O>[CH3:15][C:12]1([CH3:16])[O:11][C@H:10]2[CH2:9][S:8][C@H:7]([C@H:5]([OH:6])[CH2:4][OH:3])[C@H:14]2[O:13]1참가 물질
3
실험 절차
A solution of 109 (5.4 g, 20.1 mmol) in 30% aqueous AcOH (150 mL) was stirred at room temperature for 50 h. The reaction mixture was evaporated under reduced pressure, and the resulting residue was purified by silica gel column chromatography (hexane/ethyl acetate=1:1) to give the diol 110 (3.4 g, 75%) as a syrup: 1H NMR (CDCl3) δ 1.34 (s, 3H, CH3), 1.53 (s, 3H, CH3), 2.90 (dd, 1H, J=12.9, 2.2 Hz, 6′-CHH), 3.09 (dd, 1H, J=12.9, 4.8 Hz, 6′-CHH), 3.27 (dd, 1H, J=7.8, 1.9 Hz, 4′-H), 3.49 (br s, 2H, 2×OH), 3.58–3.72 (m, 2H, HOCHHCH(OH)), 3.79 (dd, 1H, J=11.0, 2.9 Hz, HOCHH), 4.93 (m, 2H, 3a-H, 6a-H); Anal. Calcd for C19H16O4S: C, 49.07; H, 7.32; S, 14.56 . Found: C, 49.24; H, 7.72; S, 14.23.