4-Nitroaniline → N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide

HRID 1268817노트

반응식

HRID 1268817 반응식
[N+:1]([C:4]1[CH:10]=[CH:9][C:7]([NH2:8])=[CH:6][CH:5]=1)([O-:3])=[O:2].[Cl:11][CH2:12][CH2:13][CH2:14][S:15](Cl)(=[O:17])=[O:16]>N1C=CC=CC=1>[N+:1]([C:4]1[CH:10]=[CH:9][C:7]([NH:8][S:15]([CH2:14][CH2:13][CH2:12][Cl:11])(=[O:17])=[O:16])=[CH:6][CH:5]=1)([O-:3])=[O:2]

참가 물질

4

반응물 2

HCID 74754-NitroanilineHCID 154103-Chloropropanesulphonyl chloride

생성물 1

HCID 17988807N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

A solution of 5.00 g (36.2 mmol) of 4-nitroaniline and 6.41 g (36.2 mmol) of 3-chloropropanesulfonyl chloride in 20 ml of pyridine is stirred overnight at room temperature. The reaction mixture is then poured onto ice. The precipitate which deposits in the process is filtered off with suction and dried, giving N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide as a yellowish solid; ESI 279.

후처리

  1. additionThe reaction mixture is then poured onto ice
  2. filtrationis filtered off with suction
  3. customdried

출처 및 근거

ORD 기록
ord-dad8a22826ee4ef1ae0115a041e9ed1e
출처 데이터셋
uspto-grants-2007_04
특허 번호
US07199133B2

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