Water → HCID 73446014, 화합물
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[N-:1]=[N+:2]=[N-:3].[Na+].O.[C:6]([C:8]([C:13]1[S:14][CH:15]=[CH:16][CH:17]=1)=[CH:9][C:10](Cl)=[O:11])#[N:7]>O1CCOCC1>[C:6]([C:8]([C:13]1[S:14][CH:15]=[CH:16][CH:17]=1)=[CH:9][C:10]([N:1]=[N+:2]=[N-:3])=[O:11])#[N:7]참가 물질
5
실험 절차
To a vigorously stirring suspension of NaN3 (55 g, 0.85 mol) in 1:1; dioxane:H2O (200 mL) cooled to 0° C. was added dropwise over 20 min a solution of 3-cyano-3-thiophen-2-yl-acryloyl chloride 22 (84.3 g, 0.428 mol) in dioxane (150 mL). After stirring at 0° C. for 20 min, the reaction was warmed to room temperature and stirred for 1 h. To the reaction solution was added 600 mL H2O, thus producing a precipitate which was filtered, washed with H2O and dried under vacuum to provide pure 85 g of 23.
후처리
- stirringAfter stirring at 0° C. for 20 min
- stirringstirred for 1 h
- customthus producing a precipitate which
- filtrationwas filtered
- washwashed with H2O
- customdried under vacuum
출처 및 근거
- ORD 기록
- ord-f7129030e1304c0a932a08e81d0c1c7b
- 출처 데이터셋
- uspto-grants-2007_04
- 특허 번호
- US07199119B2
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