Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroform → N-(7-ethoxy-1,3,4,9-tetrahydro-2H-carbazol-2-yl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | Iodoethane | HCID 6340 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | N-(1,3,4,9-tetrahydro-7-hydroxy-2H-carbazol-2-yl)acetamide | HCID 20529233 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-(7-ethoxy-1,3,4,9-tetrahydro-2H-carbazol-2-yl)acetamide | HCID 20529245 | — |
반응 단계
A mixture of 0.02 mol of N-(1,3,4,9-tetrahydro-7-hydroxy-2H-carbazol-2-yl)acetamide, 0.022 mol of ethyl iodide, 0.022 mol of anhydrous K2CO3, and 50 ml of Me2CO was stirred and refluxed for 48 hr. Sufficient CHCl3 and H2O were added to the cooled reaction mixture to give two clear layers. The CHCl3 layer was washed with 1 N NaOH, H2O, dried, evaporated, and the resulting solid residue was recrystallized from i-PrOH to give the title compound, mp 184°-186°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04254134 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-9c73945c65274a80b3d8e1aaa760b5f1 |
| 출처 메모 | uspto-grants-1981_03 |