4,6-dichloro-N-phenyl-1,3,5-triazin-2-amine → HCID 9923909, 화합물

HRID 1269374노트

반응식

HRID 1269374 반응식
[Cl:1][C:2]1[N:7]=[C:6](Cl)[N:5]=[C:4]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:3]=1.[NH2:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[CH2:22][CH2:21][CH2:20]2>>[Cl:1][C:2]1[N:7]=[C:6]([NH:16][C:17]2[CH:18]=[C:19]3[C:23](=[CH:24][CH:25]=2)[CH2:22][CH2:21][CH2:20]3)[N:5]=[C:4]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:3]=1

참가 물질

3

반응물 2

HCID 167664,6-dichloro-N-phenyl-1,3,5-triazin-2-amineHCID 90496Indan-5-amine

생성물 1

HCID 9923909HCID 9923909, 화합물수율 37%

실험 절차

The reaction of 4,6-dichloro-N-phenyl-[1,3,5]triazine-2-amine with 5-aminoindan using the method described for the synthesis of CT-32028 provided CT-32099 (36 mg, 37% yield). 1H NMR (d6-DMSO) δ 10.15–10.28 (m, 2H), 7.56–7.72 (m, 3H), 7.05–7.39 (m, 5H), 2.75–90 (m, 4H), 1.94–2.09 (m, 2H).

후처리

  1. customdescribed for the synthesis of
  2. customCT-32028 provided

출처 및 근거

ORD 기록
ord-dc056df1cf8d4331b189cbf940263384
출처 데이터셋
uspto-grants-2007_04
특허 번호
US07199238B2

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