Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromo-3-methylbutane → 15-Methylhexadecyl bromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromo-3-methylbutane | HCID 7891 | — |
| 반응물 | 1,12-Dibromododecane | HCID 18766 | — |
| 반응물 | Magnesium | HCID 5462224 | — |
| 촉매 | Copper;dilithium;tetrachloride | HCID 193501 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 15-Methylhexadecyl bromide | HCID 20437385 | — |
| 생성물 | HCID 178418529 | HCID 178418529 | — |
반응 단계
A solution of 3-methylbutylmagnesium bromide is prepared by treating 15 g. (0.1 mole) 3-methylbutyl bromide with 2.7 g. (1.1 eq) magnesium turnings in 50 ml. dry tetrahydrofuran. The resultant Grignard reagent is dropwise added to a cold (-10° C.) solution of 36.1 g. (1.1 eq) 1,12-dibromododecane and 0.2 g. (1 m mole) dilithiumtetrachloro cuprate in 75 ml. dry tetrahydrofuran. The solution is stirred for one hour, evaporated, and fractionally distilled in vacuo to yield 15-methylhexadecylbromide as a colorless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04254138 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-4b450992ea5c48be9f42825b1c6d7949 |
| 출처 메모 | uspto-grants-1981_03 |