6-methyl-1H-indazol-5-ol → 6-methyl-5-(piperidin-4-yloxy)-1H-indazole

HRID 1269824

반응식

HRID 1269824 반응식
C(OC1C=C2[C:11](=[CH:12][C:13]=1C)[N:10]([C:15](=O)[CH3:16])N=C2)(=O)C.[CH3:18][C:19]1[CH:27]=[C:26]2[C:22]([CH:23]=[N:24][NH:25]2)=[CH:21][C:20]=1[OH:28]>>[CH3:18][C:19]1[CH:27]=[C:26]2[C:22]([CH:23]=[N:24][NH:25]2)=[CH:21][C:20]=1[O:28][CH:13]1[CH2:12][CH2:11][NH:10][CH2:15][CH2:16]1

참가 물질

3

반응물 2

HCID 229340186-methyl-1H-indazol-5-olHCID 694307581-acetyl-6-methyl-1H-indazol-5-yl acetate

생성물 1

HCID 229335796-methyl-5-(piperidin-4-yloxy)-1H-indazole

실험 절차

The following compound of Example 406 was synthesized by carrying out reactions according to the methods described in Example 372, (b) and Example 377, except for using the 6-methyl-1H-indazol-5-ol synthesized in Example 403, as a starting material.

출처 및 근거

ORD 기록
ord-4ff30137941c4520b6dac0ea2e01445b
출처 데이터셋
uspto-grants-2007_04
특허 번호
US07199147B2

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