4-methyl-1H-indazol-5-ol → HCID 178431636, 화합물
반응식
[NH:1]1[C:9]2[C:4](=[CH:5][C:6](O[C@@H]3CCC[C@H](N4C(=O)C5C(=CC=CC=5)C4=O)C3)=[CH:7][CH:8]=2)C=N1.O[C@@H]1CCC[C@H](N2C(=O)C3C(=CC=CC=3)C2=O)C1.[CH3:46][C:47]1[C:55]([OH:56])=[CH:54][CH:53]=[C:52]2[C:48]=1[CH:49]=[N:50][NH:51]2>>[CH3:46][C:47]1[C:55]([O:56][C@H:6]2[CH2:5][CH2:4][C@H:9]([NH2:1])[CH2:8][CH2:7]2)=[CH:54][CH:53]=[C:52]2[C:48]=1[CH:49]=[N:50][NH:51]2참가 물질
4
실험 절차
The following compound of Example 409 was synthesized by carrying out reaction according to the method described in Example 385, except for using the cis-2-[3-(1H-indazol-5-yloxy)cyclohexyl]-1H-isoindole-1,3(2H)-dione obtained in Example 326, (d) and the 4-methyl-1H-indazol-5-ol obtained in Example 402, as starting materials.