4-(Acetylamino)-2,5-dimethylphenyl acetate → trans-3-[(4-Methyl-1h-indazol-5-yl)oxy]cyclohexanamine
반응식
O[C@H:2]1[CH2:7][CH2:6][C@H:5]([N:8]2C(=O)C3C(=CC=CC=3)C2=O)[CH2:4][CH2:3]1.C(OC1C=C(C)C(NC(=O)C)=CC=1C)(=O)C.[CH3:35][C:36]1[C:44]([OH:45])=[CH:43][CH:42]=[C:41]2[C:37]=1[CH:38]=[N:39][NH:40]2>>[CH3:35][C:36]1[C:44]([O:45][C@H:3]2[CH2:2][CH2:7][CH2:6][C@H:5]([NH2:8])[CH2:4]2)=[CH:43][CH:42]=[C:41]2[C:37]=1[CH:38]=[N:39][NH:40]2참가 물질
4
실험 절차
The following compound of Example 410 was synthesized by carrying out reactions according to the methods described in Example 385 and Example 327, except for using the trans-2-(4-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione obtained in Example 323, (a) and the 4-methyl-1H-indazol-5-ol obtained in Example 402, as starting materials.
출처 및 근거
- ORD 기록
- ord-f566524dc1594179af565aba95292ddb