Methyl 3-aminocinnamate → Methyl 3-(3-aminophenyl)propanoate
반응식
[CH3:1][O:2][C:3](=[O:13])[CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([NH2:12])[CH:7]=1>C(O)C.[Pd]>[CH3:1][O:2][C:3](=[O:13])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([NH2:12])[CH:7]=1참가 물질
4
실험 절차
A mixture of 3-(3-amino-phenyl)-acrylic acid methyl ester (6 g) and 10% Pd on activated carbon (1 g) in ethanol (50 ml) was hydrogenated at 30 psi for 18 h and filtered over Celite. Removal of the volatiles in vacuo provided 3-(3-amino-phenyl)propionic acid methyl ester (6 g).
후처리
- filtrationfiltered over Celite
- customRemoval of the volatiles in vacuo
출처 및 근거
- ORD 기록
- ord-7555eef1c19c4a72872c7b55e294c982
- 출처 데이터셋
- uspto-grants-2007_04
- 특허 번호
- US07202257B2
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