p-Toluenesulfonic acid → HCID 58846560, 화합물

HRID 1271604노트

반응식

HRID 1271604 반응식
[C:1]([C:4]1[O:8][N:7]=[C:6]([O:9][CH2:10][C:11]([OH:13])=[O:12])[CH:5]=1)([OH:3])=[O:2].[C:14]1(C)C=CC(S(O)(=O)=O)=C[CH:15]=1>C(O)C>[C:1]([C:4]1[O:8][N:7]=[C:6]([O:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:5]=1)([OH:3])=[O:2]

참가 물질

4

반응물 2

HCID 6101p-Toluenesulfonic acidHCID 111481453-(Carboxymethoxy)isoxazole-5-carboxylic acid

생성물 1

HCID 58846560HCID 58846560, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

(5-Carboxyisoxazol-3-yl)oxyacetic acid (4.0 mmol, Example 74) is dissolved in ethanol (50 mL), to which is added a catalytic amount of p-toluenesulfonic acid (100 mg). After stirring overnight at room temperature, the ethanol was removed and the residue was recrystallized from ethanol/water.

후처리

  1. customthe ethanol was removed
  2. customthe residue was recrystallized from ethanol/water

출처 및 근거

ORD 기록
ord-86201a8f870742149380140085d3df1a
출처 데이터셋
uspto-grants-2007_04
특허 번호
US07205403B2

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