3-(2,6dichloro-4-(benzyloxy)phenoxy)-1-propyl alcohol → HCID 18454988, 화합물
반응식
[Cl:1][C:2]1[CH:12]=[C:11]([O:13]CC2C=CC=CC=2)[CH:10]=[C:9]([Cl:21])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][OH:8].[H][H]>[Pd].C(O)C>[Cl:1][C:2]1[CH:12]=[C:11]([OH:13])[CH:10]=[C:9]([Cl:21])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][OH:8]참가 물질
5
실험 절차
This compound was prepared in a manner analogous to that of Step B of Example 1, by the treatment of 11.8 grams (0.036 mole) of 3-[2,6-dichloro-4-(phenylmethoxy)phenoxy]propan-1-ol with hydrogen gas in the presence of a catalytic amount of 10% palladium on carbon in ethanol using a Parr hydrogenation apparatus. Following the theoretical uptake of hydrogen, the reaction mixture was and filtered and concentrated under reduced pressure to a residue, yielding 8.0 grams of the subject compound.
후처리
- customThis compound was prepared in a manner analogous to that of Step B of Example 1
- filtrationfiltered
- concentrationconcentrated under reduced pressure to a residue
출처 및 근거
- ORD 기록
- ord-3657d23dd5754bba8161abf3a73df7d6
- 출처 데이터셋
- uspto-grants-2007_04
- 특허 번호
- US07208450B2
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