1-(3-Hydroxy-2,2,4,6,7-pentamethyl-3-(3-thienyl)-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methoxyphenyl)piperazine → HCID 10183186, 화합물
반응식
O[C:2]1([C:30]2[CH:34]=[CH:33][S:32][CH:31]=2)[C:6]2[C:7]([CH3:27])=[C:8]([N:13]3[CH2:18][CH2:17][N:16]([C:19]4[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=4)[CH2:15][CH2:14]3)[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4][C:3]1([CH3:29])[CH3:28]>C(O)C>[CH3:28][C:3]1([CH3:29])[CH:2]([C:30]2[CH:34]=[CH:33][S:32][CH:31]=2)[C:6]2[C:7]([CH3:27])=[C:8]([N:13]3[CH2:18][CH2:17][N:16]([C:19]4[CH:20]=[CH:21][C:22]([O:25][CH3:26])=[CH:23][CH:24]=4)[CH2:15][CH2:14]3)[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4]1참가 물질
3
실험 절차
Using 1-(3-hydroxy-2,2,4,6,7-pentamethyl-3-(3-thienyl)-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methoxyphenyl)piperazine obtained in Example 36, the title compound was synthesized in the same manner as in Example 46. Yield 77%. mp. 128–131° C. (ethanol).
출처 및 근거
- ORD 기록
- ord-98bd575cbdc64ac3998c4bd8ea294230
- 출처 데이터셋
- uspto-grants-2007_04