Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4-Hydroxyphenoxy)acetic acid → 2-(4-Hydroxy-phenoxy)-N-[2-(1H-indol-2-yl)-phenyl]-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4-Hydroxyphenoxy)acetic acid | HCID 15881 | — |
| 반응물 | 2-(2-Aminophenyl)indole | HCID 735966 | — |
| 생성물 | 2-(4-Hydroxy-phenoxy)-N-[2-(1H-indol-2-yl)-phenyl]-acetamide | HCID 18455693 | 30% |
반응 단계
Prepared from 2-(2-aminophenyl) indole and (4-hydroxyphenoxy) acetic acid in 30% yield following procedure 1. The product was crystallized from methanol. 89% Purity by LC/MS (230 DAD), Mass-spec [M+H+]=359, 1H NMR (MeOH-d4): 4.52 s (2H), 6.55 d, 9 Hz (2H), 6.58 s (1H), 6.61 d, 9 Hz (2H), 7.09 t, 8 Hz (1H), 7.18 t, 8 Hz (1H), 7.26 t, 8 Hz (1H), 7.37–7.43 m (2H), 7.56 t, 8 Hz (2H), 8.38 d, 8 Hz (1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07208493B2 |
| 출처 데이터셋 | uspto-grants-2007_04 |
| ORD ID | ord-bdcd75312f5f440fba6a02cf1fa5282a |
| 출처 메모 | uspto-grants-2007_04 |