3-(Trifluoromethyl)benzyl chloride → HCID 13037796, 화합물

HRID 127249

반응식

HRID 127249 반응식
[OH:1][CH:2]([CH2:10][O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH2:5]1.[F:28][C:29]([F:39])([F:38])[C:30]1[CH:31]=[C:32]([CH:35]=[CH:36][CH:37]=1)[CH2:33]Cl>>[F:28][C:29]([F:38])([F:39])[C:30]1[CH:31]=[C:32]([CH:35]=[CH:36][CH:37]=1)[CH2:33][N:7]1[CH2:8][CH2:9][N:4]([CH2:3][CH:2]([OH:1])[CH2:10][O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:5][CH2:6]1

참가 물질

3

반응물 2

HCID 697163-(Trifluoromethyl)benzyl chlorideHCID 130377901-(2-Hydroxy-3-n-hexadecyloxypropyl)-piperazine

생성물 1

HCID 13037796HCID 13037796, 화합물

실험 절차

Following the procedure of Example 5, 1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine was reacted with 3-(trifluoromethyl)benzyl chloride to form 1-(3-trifluoromethylbenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)piperazine, mp 133°-135° C.

출처 및 근거

ORD 기록
ord-4c3209023b76405cace4f52bfb4581c5
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04255426

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