반응식
C([N:8]1[CH2:18][CH2:17][C:11]2([O:15][C:14](=[O:16])[NH:13][CH2:12]2)[CH2:10][CH2:9]1)C1C=CC=CC=1>[Pd].C(O)C>[O:15]1[C:11]2([CH2:10][CH2:9][NH:8][CH2:18][CH2:17]2)[CH2:12][NH:13][C:14]1=[O:16]참가 물질
4
실험 절차
A mixture of 6.2 g 8-benzyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one, 50 ml ethanol and 0.5 g, 10% palladium on carbon is hydrogenated at 60 psi and 50° for 18 hours. After filtration and removal of solvent there is obtained 4.2 g 1-oxa-3,8-diazaspiro[4.5]decan-2-one, mp 158°-161°.
후처리
- filtrationAfter filtration and removal of solvent
출처 및 근거
- ORD 기록
- ord-62b2008bddf045bea21e728225fb9c48
- 출처 데이터셋
- uspto-grants-1981_03
- 특허 번호
- US04255432
연결된 노트
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