참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Chlorosulfonic acid | HCID 24638 | — |
| 반응물 | 2,3-Dihydro-1,4-benzodioxin-5-carboxylic acid | HCID 78184 | — |
| 생성물 | 7-(Chlorosulphonyl)-2,3-dihydro-1,4-benzodioxin-5-carboxylic acid | HCID 6455316 | 93.5% |
반응 단계
670 g of chlorosulfonic acid were introduced into a balloon flask provided with a condenser and a thermometer. 173 g of 1,4-benzodioxane-5-carboxylic acid were added in portions with the temperature being maintained at 5°-10° C. The mixture was heated at 55° C. and then cooled and poured into ice. The precipitate was dried off, washed and dried again. 250 g of 7-chlorosulfonyl-1,4-benzodioxane-5-carboxylic acid were obtained (M.P.: 210°-215° C.; yield: 93.5%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04255580 |
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| 출처 데이터셋 | uspto-grants-1981_03 |
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| ORD ID | ord-0bdad6f393eb40bfb277d8fb0bb16f6a |
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| 출처 메모 | uspto-grants-1981_03 |
|---|
