Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl-7-methylsulfamoyl-1,4-benzodioxane-5-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Sodium Carbonate | HCID 10340 | — |
| 반응물 | 2,3-Dihydro-7-(N-methylsulphamoyl)-1,4-benzodioxin-5-carboxylic acid | HCID 6455317 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Methyl-7-methylsulfamoyl-1,4-benzodioxane-5-carboxylate | HCID 54343297 | 85% |
반응 단계
750 ml of methanol were introduced into a balloon flask provided with a condenser. Then, under cooling, 273 g of concentrated sulfuric acid and 160 g of 7-methylsulfamoyl-1,4-benzodioxane-5-carboxylic acid were added. The mixture was heated under reflux, cooled and poured into water and sodium carbonate. The precipitate was dried off, washed and dried. 143 g of methyl-7-methylsulfamoyl-1,4-benzodioxane-5-carboxylate were obtained (M.P.: 159°-160° C.: yield: 85%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04255580 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-6064d75672864123861b447ab232f637 |
| 출처 메모 | uspto-grants-1981_03 |