Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Methylpyrrolidine-2-methylamine → N-(1-methyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Methylpyrrolidine-2-methylamine | HCID 117300 | — |
| 반응물 | 7-Methylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride | HCID 20544720 | — |
| 생성물 | N-(1-methyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide | HCID 24834936 | 77% |
반응 단계
In a similar manner to that of the above example, 71 g of levorotatory 1-methyl-2-aminomethyl-pyrrolidine was reacted with 180.5 g of 7-methylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride to give 175 g of levorotatory-N-(1-methyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide (M.P.: 187°-187.5° C.; yield: 77%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04255580 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-772f9aff10c54927bf8ad6f38c6f8246 |
| 출처 메모 | uspto-grants-1981_03 |