Sulfuryl chloride → HCID 178472913, 화합물
반응식
[OH:1]/[N:2]=[C:3](/[C:9](=[O:12])[CH2:10][CH3:11])\[C:4]([O:6][CH2:7][CH3:8])=[O:5].S(Cl)([Cl:16])(=O)=O>C(O)(=O)C>[Cl:16][CH:10]([CH3:11])[C:9](=[O:12])/[C:3](=[N:2]/[OH:1])/[C:4]([O:6][CH2:7][CH3:8])=[O:5]참가 물질
4
실험 절차
A solution of ethyl 2-(Z)-hydroxyimino-3-oxopentanoate (10 g) in 10 ml of acetic acid was cooled to 0° C. and treated dropwise with sulfuryl chloride (5.3 ml). The mixture was stirred for 3 hours at room temperature and quenched by ice-water. The mixture was extracted with ethyl acetate, and the extracts were washed with brine and dried with magnesium sulfate. The solvent was removed under reduced pressure to afford ethyl 4-chloro-2-(Z)-hydroxyimino-3-oxopentanoate (11.97 g).
후처리
- customquenched by ice-water
- extractionThe mixture was extracted with ethyl acetate
- washthe extracts were washed with brine
- dry with materialdried with magnesium sulfate
- customThe solvent was removed under reduced pressure
출처 및 근거
- ORD 기록
- ord-b987128ad09f45c084a804ee622b1dcc
- 출처 데이터셋
- uspto-grants-2000_12
- 특허 번호
- US06159961
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