Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Amino-1-butanol → HCID 178526250, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Amino-1-butanol | HCID 25868 | — |
| 반응물 | Chloride 2-chloropyridinium 1-oxide | HCID 88478 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | 2-Methyl-2-butanol | HCID 6405 | — |
| 생성물 | HCID 178526250 | HCID 178526250 | — |
반응 단계
A mixture of 4-amino-1-butanol (1.76 g, 20 mmol), 2-chloropyridine N-oxide hydrochloride (3.98 g, 24 mmol), and NaHCO3 (8.40 g, 100 mmol) in tert-amyl alcohol (50 mL) is heated at reflux under argon. After 48 h, the reaction is cooled, diluted with EtOH, filtered, and concentrated. The residue is reconcentrated from toluene, and chromatographed (silica gel) to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06159964 |
| 출처 데이터셋 | uspto-grants-2000_12 |
| ORD ID | ord-3b6c24c0bc6444779df62ea104da4529 |
| 출처 메모 | uspto-grants-2000_12 |