2-(4-Bromonaphthalen-1-yl)acetic acid → 4-Bromo-N-[4-methoxy-3-(4-methylpiperizin-1-yl)phenyl]naphth-1-yl Acetamide
반응식
[Br:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH2:12][C:13]([OH:15])=O)=[CH:4][CH:3]=1.[CH3:16][O:17][C:18]1[CH:24]=[CH:23][C:21]([NH2:22])=[CH:20][C:19]=1[N:25]1[CH2:30][CH2:29][N:28]([CH3:31])[CH2:27][CH2:26]1>>[Br:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH2:12][C:13]([NH:22][C:21]2[CH:23]=[CH:24][C:18]([O:17][CH3:16])=[C:19]([N:25]3[CH2:26][CH2:27][N:28]([CH3:31])[CH2:29][CH2:30]3)[CH:20]=2)=[O:15])=[CH:4][CH:3]=1참가 물질
3
실험 절차
The title compound was prepared from 4-bromonaphth-1-ylacetic acid (J. Org. Chem., 1951, 16, 1588) and 4-methoxy-3-(4-methylpiperazin-1-yl)aniline (EP0533268A1) following a similar procedure to Example 1.
출처 및 근거
- ORD 기록
- ord-98b553b8598a463f85bfdbfb84060673
- 출처 데이터셋
- uspto-grants-2000_12
- 특허 번호
- US06159979