Acetone → HCID 20284830, 화합물

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[NH2:1][CH2:2][CH:3]1[C:15]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[NH:8][C:7]=2[S:6][CH2:5][CH2:4]1.[CH3:16][C:17]([CH3:19])=O>>[C:17](=[N:1][CH2:2][CH:3]1[C:15]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[NH:8][C:7]=2[S:6][CH2:5][CH2:4]1)([CH3:19])[CH3:16]

참가 물질

반응물 2

HCID 180Acetone

HCID 30560881-(2,3,4,9-Tetrahydrothiopyrano[2,3-b]indol-4-yl)methanamine

생성물 1

HCID 20284830HCID 20284830, 화합물

반응 조건

온도: 50 °C

실험 절차

A solution of 4-aminomethyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole (1.0 g) in acetone (10 ml) is kept at room temperature for 30 minutes and then heated at 50° C. for 5 minutes. The solution is cooled with ice. The colorless precipitate is collected by filtration to give 4-isopropylideneaminomethyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole (1.07 g) melting at 173° C. (decomp.).

후처리

temperatureThe solution is cooled with ice
filtrationThe colorless precipitate is collected by filtration

출처 및 근거

ORD 기록: ord-fc5f5bafeac746ba955f7fee1b028f4a
출처 데이터셋: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04256640

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