4-Vinylbenzoic acid → 4-Vinylbenzoyl chloride

HRID 1276007

반응식

HRID 1276007 반응식
[CH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][CH:4]=1)=[CH2:2].C(Cl)(=O)C([Cl:15])=O>C1C=CC=CC=1>[CH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([Cl:15])=[O:8])=[CH:5][CH:4]=1)=[CH2:2]

참가 물질

4

반응물 2

HCID 140984-Vinylbenzoic acidHCID 65578Oxalyl chloride2회

생성물 1

HCID 110520284-Vinylbenzoyl chloride

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

To a clean round bottom flask with an argon atmosphere and equipped with magnetic stir bar is added para-vinyl benzoic acid (10 g, 0.067 mole) which is suspended in benzene (25 ml). Oxalyl chloride (25 g, 0.197 mole) is added to the flask. The mixture is stirred for 8 hours and continuously flushed with a continuous stream of argon to purge the system of the gases generated during the reaction. Solvent and excess oxalyl chloride is stripped off under vacuum. Finally, the product is distilled under vacuum to yield para-vinyl benzoyl chloride. Approximately 90% of the theoretical yield is obtained.

후처리

  1. customTo a clean round bottom flask with an argon atmosphere and equipped with magnetic stir bar
  2. customcontinuously flushed with a continuous stream of argon
  3. customto purge the system of the gases
  4. customgenerated during the reaction
  5. distillationFinally, the product is distilled under vacuum

출처 및 근거

ORD 기록
ord-a6f780e46b504b7696f373ceaed9c44b
출처 데이터셋
uspto-grants-2000_12
특허 번호
US06165457

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