(5-Methylpyridin-2-yl)methanol → 2-Pyridinemethanol, 5-ethyl-

HRID 1276069노트

반응식

HRID 1276069 반응식
OCC1C=CC(C)=CN=1.C([O:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH3:22])=[CH:17][N:16]=1)(=O)C>>[OH:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH3:22])=[CH:17][N:16]=1

참가 물질

3

반응물 2

HCID 12325387(5-Methylpyridin-2-yl)methanolHCID 14346253(5-Ethylpyridin-2-yl)methyl acetate

생성물 1

HCID 30139422-Pyridinemethanol, 5-ethyl-수율 85%

실험 절차

This synthesis was performed analogously to the synthesis reported for 2-hydroxymethyl-5-methyl pyridine. Starting from 2-acetoxymethyl-5-ethyl pyridine (40 g, 223 mmol), pure 2-hydroxymethyl-5-ethyl pyridine (26.02 g, 189 mmol, 85%) was obtained as a slightly yellow oil.

출처 및 근거

ORD 기록
ord-281d65d3f1b4486fb75b892a9482bc7e
출처 데이터셋
uspto-grants-2000_12
특허 번호
US06165963

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