2-(2-Chloroethoxy)tetrahydro-2H-pyran → 1-(2-Hydroxy-1-ethyl)-3,3,7-trimethyl-1,3-dihydro-2H-indol-2-one

반응식

[CH3:1][C:2]1([CH3:13])[C:10]2[C:5](=[C:6]([CH3:11])[CH:7]=[CH:8][CH:9]=2)[NH:4][C:3]1=[O:12].Cl[CH2:15][CH2:16][O:17]C1CCCCO1>>[OH:17][CH2:16][CH2:15][N:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][C:6]=2[CH3:11])[C:2]([CH3:13])([CH3:1])[C:3]1=[O:12]

참가 물질

반응물 2

HCID 2549512-(2-Chloroethoxy)tetrahydro-2H-pyran

HCID 151874723,3,7-Trimethyl-1,3-dihydro-2H-indol-2-one

생성물 1

HCID 221161181-(2-Hydroxy-1-ethyl)-3,3,7-trimethyl-1,3-dihydro-2H-indol-2-one

실험 절차

Prepared from 3,3,7-trimethyl-1,3-dihydro-2H-indol-2-one (prepared by the method of Endler and Becker; Organic Syntheses Coll. vol. 4 page 657) and 2-(2-chloroethoxy)tetrahydro-2H-pyran as described above.

후처리

customprepared by the method of Endler and Becker

출처 및 근거

ORD 기록: ord-e92c76d4f1cd4485877c8e5ec2076384
출처 데이터셋: uspto-grants-2000_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06166040

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