Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-Isoxazolamine, 5-(1,1-dimethylethyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Pentanenitrile, 4,4-dimethyl-3-oxo- | HCID 108871 | — |
| 반응물 | Hydroxylamine, sulfate (1:1) | HCID 159255 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Isoxazolamine, 5-(1,1-dimethylethyl)- | HCID 171473 | 81.7% |
반응 단계
A suspension of pivaloylacetonitrile (12.52 g) and triethylamine (11.27 g) in water (200 ml) is stirred and mixed with hydroxylamine sulfate (9.03 g). pH 8.22. The reaction mixture is treated as in Example 2 to give 3-amino-5-t-butylisoxazole (11.45 g; yield, 81.7%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04256899 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-d73c023895844ceaa0b5ec960b928bde |
| 출처 메모 | uspto-grants-1981_03 |