Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Aminopentan-1-ol → 2-(5-Hydroxypentyl)amino-2-oxoethoxylacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Aminopentan-1-ol | HCID 75634 | — |
| 반응물 | 1,4-Dioxane-2,6-dione | HCID 78232 | — |
| 반응물 | Methanesulfonate | HCID 85257 | — |
| 생성물 | 2-(5-Hydroxypentyl)amino-2-oxoethoxylacetic acid | HCID 20285862 | — |
반응 단계
methanesulfonate by the following sequence of steps: (a) by reacting diglycolic anhydride and 5-aminopentanol to produce [2-(5-hydroxypentyl)amino-2-oxoethoxylacetic acid, (b) heating to cyclize the latter to obtain 4-(5-hydroxypentyl)-3,5-dioxomorpholine, (c) esterifying the latter with methanesulfonyl chloride to produce 5-(3,5-dioxomorpholino)pentyl methanesulfonate and (d) reacting the mesylate with 2-benzhydrylpiperidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04256891 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-144787c7592949a3b5fbc70ae64e01f9 |
| 출처 메모 | uspto-grants-1981_03 |